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Immune and Gene Engineering Laboratory (IGEN Lab)

We aim to advance current therapeutic technologies and translate lab discoveries into effective, innovative treatments.

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Research

We seek to develop groundbreaking solutions for unmet medical needs through interdisciplinary research at the intersection of nanoparticle/molecular engineering, immune engineering, and gene therapy. We focus on the following key areas:

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1) Utilizing nanoengineering and molecular engineering to create novel approaches for immune cell reprogramming

 

2) Advancing next-generation gene editing and gene therapy through innovations in non-viral delivery systems

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3) Employing fundamental principles of immunology, gene therapy, and pharmaceutical sciences to develop new therapeutic strategies for cancer, infectious, and autoimmune/inflammatory diseases 

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Latest Publications

Metalloimmunotherapy: A new class of immunotherapy

Metal ions play crucial roles in the regulation of immune pathways. In fact, metallodrugs have a long record of accomplishment as effective treatments for a wide range of diseases. Here we argue that the modulation of interactions of metal ions with molecules and cells involved in the immune system forms the basis of a new class of immunotherapies. 

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